SEROLOGICAL SURVEY OF HANTAVIRUS IN INHABITANTS FROM TROPICAL AND SUBTROPICAL AREAS OF BRAZIL




Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours

Abstract Background There are multiple copies of mitochondrial DNA (mtDNA) present in each cell type, and they are strictly regulated in a cell-specific manner by a group of nuclear-encoded mtDNA-specific replication factors.This strict regulation of mtDNA copy number is mediated by cell-specific DNA methylation of these replication factors.Gliobla

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Reduced Numerical Modeling of Turbulent Flow with Fully Resolved Time Advancement. Part 1. Theory and Physical Interpretation

A multiscale modeling concept for numerical 9x11 pergola simulation of multiphysics turbulent flow utilizing map-based advection is described.The approach is outlined with emphasis on its theoretical foundations and physical interpretations in order to establish the context for subsequent presentation of the associated numerical algorithms and the

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